LLR APC Meeting Minutes – May 2026(431 KB) - LMSG/LLR APC minutes
Date added: 4th Jun 2026
| Drug Name | Classification | Clinical Indication | Comments |
|---|---|---|---|
| ACLIDINIUM (Eklira Genuair®) | Green | COPD |
The LLR COPD guidelines have been updated (June 2026) and LAMAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| ACLIDINIUM / FORMOTEROL INHALER (Duaklir Genuair®) | Green | COPD |
1st Choice Dry Powder COPD: In line with LLR COPD guidelines Asthma: Not licensed. Can be used in people with renal impairment with no concern. In use shelf-life: 2 months
|
| APOMORPHINE - SUBLINGUAL (Kynmobi®) (NEW) | Orange | Idiopathic Parkinson’s Disease | |
| Atogepant (Aquipta®) (UPDATED) | Green | Prophylaxis of migraine |
For preventing migraine in adults who have at least 4 migraine days per month and if at least 3 different classes of preventative medicines have not worked, or are not tolerated, or are unsuitable due to safety concerns. See NICE TA973 for full details. To be prescribed in line with the LLR Migraine pathway |
| AZELAIC ACID 15% (Finacea®) (NEW) | Green | Acne | |
| BECLOMETASONE DIPROPIONATE Extra fine / FORMOTEROL (Fostair NEXThaler®) | Green |
Asthma COPD |
2nd Choice Dry Powder |
| BECLOMETASONE EXTRA-FINE / FORMOTEROL (Fostair pMDI®) | Green | Asthma & COPD |
The LLR asthma guidelines have been updated (May 2024). Fostair pMDI is no longer recommended as an option. Please review all patients to see if they can be changed to a formulary choice dry powder inhaler device in the first instance. Where an MDI device is required please review to Luforbec in line with guidance. The LLR COPD guidelines have been updated (June 2026) and ICS/LABA combinations are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| BECLOMETASONE EXTRA-FINE/ FORMOTEROL (Luforbec pMDI®) | Green | Asthma and COPD |
1st choice aerosol Management of Asthma in Adults LLR Adult Asthma Guideline (≥18 years) AIR and MART FAQ The LLR COPD guidelines have been updated (June 2026) and ICS/LABA combinations are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| BENZOYL PEROXIDE 3% / CLINDAMYCIN 1% GEL (Duac Once daily®) | Green | Acne |
Antimicrobial Guide – Acne Vulgaris |
| BENZOYL PEROXIDE 5%/ CLINDAMYCIN 1% GEL (Duac Once daily®) | Green | Acne |
Antimicrobial Guide – Acne Vulgaris |
| BUDESONIDE / FORMOTEROL (DuoResp Spiromax®) | Green | Asthma & COPD |
For adults 18 years and over. No new initiations. Continued prescribing for established, well controlled patients only. Must be used regularly for maximum benefit; twice a day dosing. The 160/4.5 strength is licensed to be prescribed as maintenance and reliever therapy (MART). LLR Adult Asthma Guideline (≥18 years) AIR and MART FAQ The LLR COPD guidelines have been updated (June 2026) and ICS/LABA combinations are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| BUDESONIDE FOAM ENEMA (Budenofalk®) | Green |
Budesonide rectal foam. To be used as an alternative to prednisolone enemas. Please note, predisolone enemas are currently significantly more expensive than budesonide |
|
| BUDESONIDE SUPPOSITORIES (NEW) | Green |
FIRST CHOICE To be used as an alternative to prednisolone suppositories. Please note, prednisolone suppositories are currently significantly more expensive than budesonide |
|
| BUDESONIDE/ FORMOTEROL (Fobumix Easyhaler®) | Green | Asthma & COPD |
Management of Asthma in Children and Young People aged 12-17 years |
| BUDESONIDE/ FORMOTEROL (Symbicort Turbohaler®) | Green | Asthma & COPD |
3rd Choice Dry Powder Management of Asthma in Adults Management of Asthma in Children aged 5-11 years Management of Asthma in Children and Young People aged 12-17 years LLR Adult Asthma Guideline (≥18 years) AIR and MART FAQ The LLR COPD guidelines have been updated (June 2026) and ICS/LABA combinations are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| BUDESONIDE/ GLYCOPYRRONIUM/ FORMOTEROL 5/7.2/160 (Trixeo Aerosphere® MDI) (NEW) | Green | COPD |
1st Choice Aerosol New patients should be initiated on Trixeo (low carbon option) COPD: In line with LLR COPD guidelines Asthma: Not licensed In use shelf-life: 3 months |
| CIPROFLOXACIN LIQUID | Green |
As per recommendations in LLR antimicrobial guidelines. Particular formulation listed stocked in Omcare service in primary care for when prescribed by PTCDA and virtual ward teams |
|
| CO-TRIMOXAZOLE TABLETS (NEW) | Green |
As per recommendations in LLR antimicrobial guidelines. Particular formulation listed stocked in Omcare service in primary care for when prescribed by PTCDA and virtual ward teams |
|
| COAGUCHEK XS PATIENT TEST STRIPS (NEW) | Green | INR Testing |
For patients who have been assessed as suitable for near patient testing by the clinician responsible for their care Patients should be advised no to invest in a meter before they have spoken to the clinician responsible for their care. CoaguChek meters are not funded by the NHS – patients are required to purchase their own after a discussion with the clinician responsible for their care. |
| Cytisine 1.5mg Tablets (NEW) | Red | For smoking cessation |
Inpatient initiation by hospital stop smoking teams only.
Short-term, 25 day course. Full course to be dispensed at, or, prior to discharge. Patient followed up by the hospital stop smoking team during inpatient stay and after discharge.
In case of treatment failure, the treatment should be discontinued and may be resumed after 2 to 3 months
|
| DAPAGLIFLOZIN (UPDATED) | Yellow | Chronic Heart failure with preserved ejection fraction and reduced ejection fraction |
In line with NICE TA679 and NICE TA902 |
| DUPILUMAB (Dupixent®) (NEW) | Red | For Maintenance Treatment of Uncontrolled chronic obstructive pulmonary disease with raised Blood Eosinophils |
Funding from: 24th June 2026 |
| FEZOLINETANT (Veoza®) (NEW) | Yellow | for treating moderate to severe vasomotor symptoms associated with menopause |
Usually recommended and initiated by secondary care specialists. However, primary care clinicians with a recognised specialist menopause qualification may initiate treatment. In line with NICE TA1143 Funding from: 29th June 2026.
|
| FLUTICASONE FUROATE / UMECLIDINIUM/ VILANTEROL 92/55/22 (Trelegy Ellipta® DPI) (NEW) | Green | COPD |
2nd Choice Dry Powder – Alternative DPI to Trimbow NEXThaler® COPD: In line with LLR COPD guidelines Asthma: Not licensed In use shelf-life: 6 weeks |
| FORMOTEROL (Atimos® Modulite MDI) | Green | Asthma & COPD |
COPD: The LLR COPD guidelines have been updated (June 2026) and LABAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. Asthma: formoterol should only be prescribed as part of a combination device (ICS/LABA), and a formoterol single agent inhaler should only be used in the few patients who require ciclesonide MDI as an ICS (licence > 12 years) In use shelf-life: 3 months
|
| FORMOTEROL (Easyhaler®) | Green | Asthma & COPD |
1st Choice Dry Powder COPD: The LLR COPD guidelines have been updated (June 2026) and LABAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. Asthma: formoterol should only be prescribed as part of a combination device (ICS/LABA), and a formoterol single agent inhaler should only be used in the few patients who require ciclesonide MDI as an ICS (licence > 6 years). In use shelf-life: 4 months
|
| FORMOTEROL (Oxis 12 Turbohaler®) | Green | Asthma & COPD |
2nd Choice Dry Powder COPD: The LLR COPD guidelines have been updated (June 2026) and LABAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. Asthma: formoterol should only be prescribed as part of a combination device (ICS/LABA), and a formoterol single agent inhaler should only be used in the few patients who require ciclesonide MDI as an ICS (licence > 6 years). In use shelf-life: manufacturer’s expiry date |
| FUROSEMIDE IV (NEW) | Green |
Particular formulation listed stocked in Omcare service in primary care for when prescribed by PTCDA and virtual ward teams |
|
| GLYCOPYRRONIUM / BECLOMETASONE EXTRA-FINE/ FORMOTEROL (Trimbow® MDI) | Green | Maintenance of COPD |
2nd Choice Aerosol COPD: (87/5/9 only) In line with LLR COPD guidelines Asthma: Not recommended in LLR In use shelf-life: 4 months Existing patients to remain on this. No active switching to Trixeo. |
| GLYCOPYRRONIUM/BECLOMETASONE EXTRA FINE /FORMETEROL DPI (Trimbow NEXThaler®) | Green | Maintenance treatment of adults with moderate to severe COPD |
1st Choice Dry Powder COPD: In line with LLR COPD guidelines Asthma: Not licensed. In use shelf-life: 6 weeks
|
| GUANFACINE (UPDATED) | Orange | ADHD - Adult |
Adult Full SCA and Request Form |
| IPRATROPIUM BROMIDE (Atrovent® MDI) | Green | COPD |
The LLR COPD guidelines have been updated (June 2026) and SAMAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| ISOTRETINOIN - Oral | Red | Severe acne |
Isotretinoin – changes to prescribing guidance and additional risk minimisation measures – GOV.UK Recommendations | Acne vulgaris: management | Guidance | NICE |
| LEVOFLOXACIN TABLETS (NEW) | Green |
As per recommendations in LLR antimicrobial guidelines. Particular formulation listed stocked in Omcare service in primary care for when prescribed by PTCDA and virtual ward teams. |
|
| MAINTELYTE SOLUTION (NEW) | Red | Maintenence of Fluid | |
| METHYLPHENIDATE (UPDATED) | Orange | Excessive sleepiness caused by narcolepsy | |
| METHYLPHENIDATE (Tuzulby®) prolonged-release chewable tablets (NEW) | Do not prescribe | ADHD | |
| METRONIDAZOLE LIQUID (NEW) | Green |
As per recommendations in LLR antimicrobial guidelines. Particular formulation listed stocked in Omcare service in primary care for when prescribed by PTCDA and virtual ward teams |
|
| NORTRIPTYLINE (NEW) | Green | Use if amitriptyline not tolerated |
Second Choice Not licensed for use in neuropathic pain. Note tablets are usually more cost effective then capsules Exception is 50mg tablets are very expensive and should not be used in LLR. It is much more cost effective to use 2 x 25mg tablets.
|
| ORALTEK (Oraltek®) (NEW) | Red | Sublingual immunotherapy for horse allergy | |
| PREDNISOLONE FOAM ENEMAS (Predfoam®) | Yellow |
Please note, significantly more expensive than budesonide foam enemas. Should be used by, or on advice from GI specialist only |
|
| PREDNISOLONE SUPPOSITORIES (UPDATED) | Green |
Please note, significantly more expensive than budesonide suppositories. Should be used by, or on advice from GI specialist only |
|
| RIMEGEPANT (Vydura®) (UPDATED) | Green | Prophylaxis of migraine |
For preventing episodic migraine in adults who have at least 4 and fewer than 15 migraine attacks per month, only if at least 3 preventative treatments have not worked in line with NICE TA906. To be prescribed in line with the LLR Migraine pathway |
| RUXOLITINIB CREAM (Opzelura®) (NEW) | Red | For Treating Non-Segmental Vitiligo in People 12 years and Over |
Funding from: 15th June 2026 |
| SACUBITRIL and VALSARTAN (Entresto®) | Yellow | Heart failure |
For use by Adult Heart Failure Clinic and Community heart failure team in line with NICE TA 388. GPs may continue prescribing
|
| SODIUM ZIRCONIUM CYCLOSILICATE (Lokelma®) (UPDATED) | Red | Acute hyperkalaemia |
FIRST CHOICE Treatment of acute hyperkalaemia, see local ED pathway. In line with NICE TA1148 Funding from: 28th July 2026 |
| SODIUM ZIRCONIUM CYCLOSILICATE (Lokelma®) (UPDATED) | Yellow | Chronic Hyperkalaemia associated with Heart failure |
Use in line with NICE TA1148 Funding from: 28th July 2026 |
| SODIUM ZIRCONIUM CYCLOSILICATE (Lokelma®) (UPDATED) | Yellow | Chronic hyperkalaemia in CKD |
In line with NICE TA1148 Funding from: 28th July 2026 Use in line with the CKD pathway |
| TIOTROPIUM (Braltus Zonda®) | Green | COPD |
The LLR COPD guidelines have been updated (June 2026) and LAMAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines.
|
| TIOTROPIUM (Spiriva HandiHaler® or Spiriva Respimat®) | Green | COPD |
The LLR COPD guidelines have been updated (June 2026) and LAMAs are no longer routinely recommended as a treatment option. No NEW initiations. For patients established on this therapy, treatment should be reviewed on a case-by-case basis, taking into account clinical stability and patient preference. Ongoing prescribing should be in line with the updated COPD guidelines. |
| TIOTROPIUM/OLODATEROL (Spiolto Respimat®) | Green | COPD |
1st Choice Aerosol COPD: In line with LLR COPD guidelines Asthma: Not licensed. Tiotropium should only be used if the expected benefit outweighs the risk in people with moderate to severe renal impairment (CrCl ≤ 50 ml/min). In use shelf-life cartridge: 3 months In use shelf-life inhaler device: 1 year (max 6 cartridges) |
| UMECLIDINIUM/ VILANTEROL 55/22 (Anoro Ellipta® DPI) (NEW) | Green | COPD |
2nd Choice Dry Powder Alternative DPI to Duaklir Genuair® (once-daily preparation) COPD: In line with LLR COPD guidelines Asthma: Not licensed Confirm patient has no co-existing asthma or atopy before prescribing. In use shelf-life: 6 weeks |
| Varenicline Tartrate | Green | Smoking cessation in adults |
Currently, there is no commissioned service within general practice to support this prescribing. This position is under review. Consequently, GPs are not obligated to issue these prescriptions. |
Recent documents from LLR APC and TAS
Date added: 4th Jun 2026
Date added: 1st Jun 2026
Date added: 1st Jun 2026
Date added: 1st Jun 2026
Date added: 27th May 2026
Date added: 20th May 2026
Date added: 12th May 2026
Date added: 12th May 2026
Date added: 12th May 2026
Date added: 12th May 2026
Date added: 12th May 2026
Date added: 6th May 2026
Date added: 12th Oct 2020
Date added: 26th Mar 2019
Date added: 17th Jan 2018
Date added: 17th Jan 2018
In common with other local health communities, the Leicester, Leicestershire and Rutland Area Prescribing Committee (LLR APC) acknowledges the benefits of having a Leicestershire Health Community-wide strategy for the prescribing of specialist medicines and the managed entry of new drugs and related technologies.
Leicestershire Health Community comprises the Leicester, Leicestershire and Rutland Integrated Care Board, University Hospitals of Leicester (UHL) NHS Trust and Leicestershire Partnership NHS Trust (LPT), amongst which there is a total consensus on the need for this strategy, and the LLR APC has been in place since 2005. Learn more